The particle leaves the second portal in a different direction to that which it entered the first. Is that significant?
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Try firing particles into the rightmost portal from different directions.
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Particles change direction when passing through portals in a clockwise manner i.e. if they enter on the right, they'll leave on the bottom, enter on the bottom and they'll leave on the left, and so on.
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You'll need to use each of the emitters to fire particles at the portal from all four different directions. After opening the central door, use the right-arrow to assist with activating the two receivers that operate the main door.